Artificial Metalloenzymes Laboratory

Endowing Organometallic Chemistry with a (Genetic) Memory
Artificial metalloenzymes result from the incorporation of an abiotic cofactor within a protein scaffold. Such hybrid catalysts combine features reminiscent of both homogeneous catalysts and enzymes.


Merging organometallic chemistry with biotechnology.

The group

Recent publications

Y. Okamoto, et al. A Cell-Penetrating Artificial Metalloenzyme Regulates a Gene Switch in a Designer Mammalian Cell. Nat. Commun. 2018. 10.1038/s41467-018-04440-0

Virtual library

Explore journals that matter to us.

Lay summary

"Catalysis is the concept which best captures the Spirit of Chemistry: the Miracle of consumption and regeneration."


Want to get in contact with us?

ArtZymes 2.0

August 9-11, 2019, Basel, Switzerland

The artificial metalloenzymes conference par excellence.